Endocrine Abstracts

Introduction: Prolactinomas are the most common pituitary tumors. Macroadenomas are rarely seen. Dopamine agonists such bromocriptin and cabergoline are the preferred treatments for prolactinomas. Herein, we report a patient with macroadenoma whose adenoma has resolved rapidly with cabergoline treatment.Case: A 49 year old male patient evaluated for weakness and headache. After detection of central hypothyroidism he was referred to our department. His pr...

Introduction: In rheumatological diseases have been observed in a rate of 0.8% of non-traumatic insufficiency fractures. The most common sites of insufficiency fractures are pelvis, sacrum, tibia, the sections near to the insertion of the fibula, calcaneus and buttocks. Generally, bone – joint involvement in rheumatic diseases and osteoporosis connected with prolonged use of corticosteroids prepares the ground for these insuffiency fractures. In this case, We aimed to pre...

Aim: Differentiated thyroid carcinomas (DTC) composes 95% of all thyroid malignancies originating from thyroid follicular epithelial cells. DTC expresses TSH receptors so long time TSH stimulation may cause cancer occurrence or malignancy progression. So we aimed to assess the role of TSH levels in predicting thyroid cancer stage or aggressiveness.Methods: We retsopectively searched thyroid cancer patients fort he last 10 years in our instution. Totally ...

Pitüitary ACTH deficiency is one cause of secondary adrenal insufficiency. Genetic factors, autoimmunity, infiltrative disease, cranial trauma can cause ACTH deficiency. Hyperpigmented skin lesions are expected in primary adrenal insufficiency while they are very rare in secondary adrenal insufficiency. Striae are characterized by linear smooth bands of atrophic appearing skin. They are mostly associated with obesity, pregnancy, hypercortisolism/Cushing syndrome. Striae a...

Introduction: Autoimmune thyroiditis (AIT), also called Hashimoto thyroiditis or chronic lymphocytic thyroiditis is characterized by destruction of the thyroid gland involving apoptosis of thyroid epithelial cells. It usually presents as euthyroidism or subclinically hypothyroidism, rarely as overt hypothyroidism. The cause of Hashimoto’s thyroiditis is thought to be a combination of genetic susceptibility and environmental factors. Bisphenol A (BPA), an endocrine-disrupt...

Extraadrenal perirenal myelolipom has been reported since 1980. In recent years, it has been reported at an increasing rate in different sites of the body ranging from the nasal cavity, mediastinum to presacral, paravesical region. However, it was the first reported case that perirenal multiple myelolipomas, each myelolipomas was about 5 cm in diameter, in associated with cortisol hypersecretion. A patient was an emigrant. She was followed in her country and was prescribed ket...

Introduction: Acute intermittent porphyria (AIP) is an autosomal dominant disorder resulting from partial deficiency of the haeme biosynthetic enzyme porphobilinogen deaminase.Case report: A 17-year-old female presented with progressive abdominal pain. She had history of recurrent abdominal pain and darkening in urine colour. She was on lansoprazol and metaclopramide, initiated 2 days earlier. She did not have additional personal or relevant family histo...

Introduction: Acromegaloidism is characterized by features of acromegaly without excessive GH secretion.Case report: A 24-year-old male presented with acral enlargement and bilateral non-inflammatory wrist and ankle pain. He had coarse facial features, prominent clubbing, enlarged hands and feet. BMI was 21.3 kg/m2. He did not have a relevant personal and family history. He was not on any medication. Due to his acromegaloid appearance he was r...

Celiac Disease (CD) is a chronic inflammatory disorder and requires life-long treatment and follow-up. Mean platelet volume (MPV), determinant of platelet function, is an independent risk factor for cardiovascular disease (CVD). Metabolic syndrome (MS) is a multiplex risk factor that arises from insulin resistance accompanying abnormal adipose deposition and function. It is a risk factor for coronary heart disease, as well as for diabetes, fatty liver, and several cancers....

Introduction: A pituitary adenoma is directly assumed to originate from anterior pituitary. It is expected that pathologies of posterior hypophysis cause diabates insipitus (DI). However recently posterior pituitary tumors (PPTs) are also declared which are not associated with DI in contrast to what is expected. Rather they have a clinical and radiologic presentation akin to anterior pituitary adenomas. Differentiation of two conditions is mainly based on pathologic immunohyst...